The course and outcome of renal failure due to human leptospirosis referred to a hospital in North of Iran A follow-up study

نویسندگان

  • Mehran Shokri Infectious Diseases and Tropical Medicine Research Center, Babol University of Medical Science, Babol, Iran.
  • Roya Ghasemian Antimicrobial Resistance Research Center, Mazandaran University of Medical Sciences,Sari,Iran.
چکیده مقاله:

Background: Renal complication of leptospirosis is common and its clinical manifestations vary from urinary sediment changes to acute renal failure. The aim of this study was to determine the final outcome of renal involvement in leptospirosis. Methods: This longitudinal prospective study included all serologically confirmed cases of leptospirosis with evidence of renal failure. All patients were followed for three months while all patients with renal failure were followed-up for one year. Results: Fifty-one patients, 53.5±14.8 years (82.4% males) with acute renal failure were studied. Over the hospitalization period, 28 patients recovered, and seven (13.72%) patients died of multiple organ failure. At the time of discharge, 16 patients had mild renal failure. Over the follow-up period, all patients recovered but in two patients renal failure persisted at creatinine level of 1.5 mg/dl. Conclusion: Development of renal failure in leptospirosis is not rare. Recovery of renal function may last several months. However, most patients recover completely at least after one year.

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منابع مشابه

the course and outcome of renal failure due to human leptospirosis referred to a hospital in north of iran a follow-up study

background: renal complication of leptospirosis is common and its clinical manifestations vary from urinary sediment changes to acute renal failure. the aim of this study was to determine the final outcome of renal involvement in leptospirosis. methods: this longitudinal prospective study included all serologically confirmed cases of leptospirosis with evidence of renal failure. all patients we...

متن کامل

The course and outcome of renal failure due to human leptospirosis referred to a hospital in North of Iran; A follow-up study.

BACKGROUND Renal complication of leptospirosis is common and its clinical manifestations vary from urinary sediment changes to acute renal failure. The aim of this study was to determine the final outcome of renal involvement in leptospirosis. METHODS This longitudinal prospective study included all serologically confirmed cases of leptospirosis with evidence of renal failure. All patients we...

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عنوان ژورنال

دوره 7  شماره None

صفحات  7- 12

تاریخ انتشار 2016-01

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