Should all Iranian Citizens Receive the Same Subsidy Rebate?

Should all patients with heart block receive biventricular pacing? All heart block patients with a pacemaker indication should receive biventricular pacing: one move, double the gains?

Should all patients receive dual chamber pacing ICDs? The rationale for the DAVID trial

All of the prospective multicenter trials that support the use of implantable defibrillators have used single chamber pacemakers/implantable cardiovertor defibrillators (ICDs). Despite the significantly increased cost of dual chamber pacemaker/ICD devices and the lack of outcome data, these devices accounted for approximately two-thirds of the ICDs implanted in the United States during the 12 m...

Should all patients with atrial fibrillation receive warfarin? Evidence from randomized clinical trials.

Anticoagulants should be used more widely in patients with atrial fibrillation. Legitimate concerns exist about the risk/benefit ratio in younger patients with no risk factors and in patients over the age of 75 years. Use of lower doses of anticoagulation (potential target range INR of 1.5-2.5) than used heretofore is probably the solution to most of the problems associated with anticoagulation...

Should all patients at high cardiovascular risk receive renin-angiotensin system blockers?

Despite considerable advances in preventative treatment during the last two decades, the increasing burden of cardiovascular (CV) disease constitutes an urgent need for new therapeutic strategies to reduce CV mortality and morbidity in patients at high CV risk. Activation of the renin-angiotensin system (RAS) results in vasoconstrictive, proliferative and pro-inflammatory effects that contribut...

Risk of venous thromboembolism and primary prophylaxis in cancer. Should all patients receive thromboprophylaxis?

Venous thromboembolism (VTE) is a common complication in patients with cancer that causes significant morbidity and mortality. Several patient-, tumour- and treatment-related risk factors for VTE in cancer patients have been identified. An effective and safe thromboprophylaxis in cancer patients at high risk of VTE is desirable. Recently, the identification of potential biomarkers and the devel...

Should all patients undergoing cardiac catheterization or percutaneous transluminal coronary angioplasty receive oxygen?

BACKGROUND Supplemental oxygen is routinely administered to patients with acute coronary syndromes. The risk of significant morbidity during cardiac catheterization or coronary angioplasty has been well described; however, to our knowledge, the need for routine oxygen supplementation in these patients has not been investigated. METHODS In phase 1, we prospectively studied 142 patients undergo...