Serum and Peritoneal Fluid CA 125 Levels Infertile Women with Pelvic Endometriosis in Urummia
نویسندگان
چکیده مقاله:
SUMMARY Infertility has a special importance in gynecology in causing social, psychological and somatic prohlems. Endometriosis is a benign but progressive disorder in reproductive life and is more common in infertile women. CA 125 is a cell membrane glycoprotein. The endometrium is one the known source of this antigen and seems to be elevated in the pelvic endometriosis. In this study, from 168 infertile women that videolaparoscopy were undertaken, 27 found to have Endometriosis. Serum and peritoneal fluid level of CA 125 were determined in these patients and control groups by RIA and EIA. Serum levels of CA 125 were within normal limits in patients and control groups. But peritoneal fluid level of CA125 in patients with Endometriosis showed markedly higher than control groups. No relation is noted between peritoneal level of CAl25 and stages of endometriosis. This study emphasizes that the peritoneal fluid levels of CA 125 is more sensitive than the serum levels and can be noted in pelvic endometriosis as a diagnostic tool.
منابع مشابه
Positive correlation between serum and peritoneal fluid CA-125 levels in women with pelvic endometriosis.
CONTEXT AND OBJECTIVE One of the diagnostic markers of endometriosis is CA-125, and elevated levels of this are caused by high concentrations in the ectopic endometrium. The objective of this study was to correlate CA-125 levels in serum and peritoneal fluid from women with and without pelvic endometriosis. DESIGN AND SETTING This was a prospective, cross-sectional, controlled study of consec...
متن کاملThe Correlation between Serum and Peritoneal Fluid CA125 Level in Women with Pelvic Endometriosis
Background Despite a high prevalence of endometriosis, there still exist many challenges in diagnosing the disease. This study aims to evaluate non-invasive and practical diagnostic methods by measuring serum and peritoneal fluid CA 125 levels in patients with endometriosis. A secondary aim is to determine the correlation between these markers with the stage of disease as well as the relationsh...
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CA-125 concentration in serum and peritoneal fluid in patients with endometriosis – preliminary results
INTRODUCTION Cancer antigen 125 (CA-125), known as a biomarker for women genital tract malignancies, could be also useful in detecting and monitoring endometriosis. The aim of this study was to evaluate CA-125 in serum and peritoneal fluid (PF) as an indicator of endometriosis. MATERIAL AND METHODS Fifty-six patients admitted to the First Department of Obstetrics and Gynaecology for diagnosti...
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عنوان ژورنال
دوره 21 شماره 1
صفحات 40- 47
تاریخ انتشار 1997-03
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