Research on C Reactive Proteins in Different Patients and Different States

C, Reactive Protein (CRP) is a serum globulin (a or /3) which reacts with the somatic antigen C-poly­saccharide of the pneumococcus in the presence of cal­cium ions in vitro, It is not a true antibody and appears nonspecifically in a wide variety of inflammatory necrotic, and infective conditions (e.g .• rheumatic fever and myo­cardial infarction).  CRP appears very early in several diseases peaks in the first few days, and falls to nondetectable levels in eight days, CRP is measurable by precipitation with a spe­cific antiserum prepared in rabbits.  CRP is not found in normal sera.  Elevation of CRP may be seen in pregnant women, and women on various oral contraceptive preparations, as well as with an IUD in place.  Our investigations during last year shows similar re­sults.