PYRAZOLINES AND ISOXAZOLINES (I). SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF P-(1-ACYL-3-METHYL-5-ARYL-4 PYRAZOLINOYL / P-(3-METHYL-5-ARYL-4ISOXAZOLINOYL) ARSANILIC ACID
نویسندگان: ثبت نشده
چکیده مقاله:
4-(acetoacetamido) arsanilic acid (II), which was then condensed with aryl aldehydes. The resulting product on reaction with hydrazine hydrate and hydroxyl amine hydrochloride yielded Pyrazolines (IV) and Isoxazolines (V), respectively. The antimicrobial activity of compounds against a number of microorganisms was evaluated. Some of these compounds showed significant antimicrobial activity
منابع مشابه
pyrazolines and isoxazolines (i). synthesis and antimicrobial activities of p-(1-acyl-3-methyl-5-aryl-4 pyrazolinoyl / p-(3-methyl-5-aryl-4isoxazolinoyl) arsanilic acid
4-(acetoacetamido) arsanilic acid (ii), which was then condensed with aryl aldehydes. the resulting product on reaction with hydrazine hydrate and hydroxyl amine hydrochloride yielded pyrazolines (iv) and isoxazolines (v), respectively. the antimicrobial activity of compounds against a number of microorganisms was evaluated. some of these compounds showed significant antimicrobial activity
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Pathogenic infections and inflammation are very common ailments humans suffer. Upsurge of resistant pathogens has impeded the antimicrobial drug development process in recent years and the search of new antimicrobial agents is clearly evident from the literature. In line with these developments the synthesis of N-substituted aryl-2-({4-[(substituted aryl carbamoyl) methyl]-5-(pyridin-4-yl)-4H-1...
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عنوان ژورنال
دوره 4 شماره 3
صفحات -
تاریخ انتشار 1993-09-01
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