Photodynamic therapy (PDT)

نویسندگان

  • Azizi, A professor, Oral Medecine Dept, faculty of Dentistry,Tehran medical sciences, Islamic Azad University, Tehran, Iran
  • Lawaf, SH Associate Professor, Prosthodontics Dept, Faculty of Dentistry, Tehran Medical Sciences
چکیده مقاله:

Photodynamic therapy (PDT) is a comparatively novel therapeutic method involving a safe light source and a light-sensitive substance, termed as photosensitizers (PSs), such as methylene blue (MB), toluidine blue (TBO), sulfonated aluminum phthalocyanine, chlorine derivatives, nontoxic indocyanine green (ICG), and curcumin (CUR). (1) The combination of a nontoxic PS with low-intensity visible light in the presence of oxygen develops reactive oxygen species (ROS) that are toxic and can cause oxidative damage to microorganisms and tumor cells. (2-4) PSs do not induce cytotoxicity but are activated by laser irradiation at a proper wavelength and develop ROS. (5,6)

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Photodynamic Therapy (PDT): PDT Mechanisms

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عنوان ژورنال

دوره 6  شماره 1

صفحات  1- 3

تاریخ انتشار 2021-01

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