P-71: Effects of Cinnamomum Verum on Sperm Parameters with High Fructose Diet Rats

Background: Obesity is a leading preventable cause of death worldwide, with increasing prevalence in adults and children. Some studies have shown that increased body mass index is related to poor semen quality, decreased sperm concentration, decreased normal-motile sperm cells and increased DNA fragmentation index. Lipid peroxidation contributes to the damage of the sperm plasma membrane. Cinnamomum verum has been used to increase sex recovery. This study also will test the effect of Cinnamomum verum extract on sperm parameters in rats with diet containing fructose pay. Materials and Methods: Wistar albino male rats, 150- 200 g divided into 3 groups: control diet during 10 weeks of study (group I), diet with high fructose (group II) and diet with high fructose treated by Cinnamomum verum extract. After 10 weeks, animals were killed and sperm parameters analysis was done. Results: The comparative evaluation between three groups revealed significant increase in sperm count in group III (49.7 × 106 per ml) rather than group II (37.8 × 106 per ml), and sperm count in group II (37.8 × 106 per ml) was reduced rather than groups I and II, significantly. as well as progressive motility of sperm in group III (44%) was higher than group I (28.5%) and group II (26.7%), but There was no significant difference between sperm morphology and viability of three groups. Conclusion: The results of this study suggested that sperm count decreases with high fructose diet and Cinnamomum verum extract could increase the sperm count and motility.