P-208: Report of A Rare Case of Endometrial Stroma Sarcoma with Sex Cord Element

Background: Endometrial stroma sarcoma (ESS) is usually formed of neoplastic cells similar to proliferative endometrial cells and comprises less than 10% of all uterine sarcomas. Presence of concurrent sex cord element with these tumors is rare. Materials and Methods: A 36 year-old woman,from yazd complaining of abnormal vaginal bleeding and history of G4P3Ab1Ch3 referred. On both occasions after clinical diagnosis of cervical polyp, biopsy specimen was taken in the out patient department and diagnosed as adenofibroma on pathological examination. The patient referred 15 months later with irregular short menstrual cycles and more severe bleeding. After hospitalization and diagnosis of a huge myomatous uterine similar to the seventh week of pregnancy after clinical examination and sonography observed,after that hysterectomy was performed. On pathological examination, low grade ESS with sex cord elements was reported. Results: ESS with sex cord elements is considered as one of the rare tumors that is from the mixed Mullerian group and clinical and pathological differential diagnosis includes polyp. Conclusion: This important point should be taken into consideration by gynecologists and pathologists during exacerbation of polypoid lesions or cervical and endometrial polyps.