P-176: Infertility and iIts Association with Helicobacter Pylori Infection

Background: Infertile couples in the reproductive failure, after a year of sex without contraception is described and in 10 to 15% of couples can be seen, that the 1/3 because of the male, 1/3 female and the rest are a common cause. Factors involved in human infertility, the expression of microbial infection (25%), biological factors, environmental and genetic (50%) and unknown causes (25%) are. Studies from 1975 until now prove that genital infections can help women suffering from infertility and in the male reproductive system, will be leading to microbial colonization of semen. The infectious agents involved in causing infertility, bacteria such as Neisseria gonorrhoea, Chlamydia trachomatis, enterobacteria, gram-positive cocci, Gardnella and Helicobacter pylori. This study investigated the relationship between Helicobacter pylori and infertility has been prepared. Materials and Methods: The present study was retrospective and by using library and Internet resources are provided. Results: Helicobacter pylori may be direct or indirect factor in infertility in both sexes. The bacteria of different ways such as oral-genital, anal-genital or oral-oral are transmitted to sexual partners or other people and often its source, the mouth, dental plaque and saliva are listed. Vaginal environment and ecological conditions of the stomach and pH are very similar and these bacteria in these conditions can be colonized. A theory that in cases of infertility by this bacterium is it have been strong antigens, which can trigger phagocytosis and Phagocyte is attracting in the region which results in severe inflammation in the uterus or fallopian tubes and followed by closure of the tube occurs or infertility may be due to production safety conditions, Ag-Ab complexes or linear homology between the bacterial protein (as Ag) with tubular human proteins. In most studies in this field, this antibody has bacteria in infertile women than fertile men. Conclusion: Due to the high H. pylori antibodies in infertile women, this bacteria can be considered as a cause of infertility in infertile men and recommended that screening tests be done on these individuals