P-166: Assisted Reproductive Techniques Outcomes in Hypogonadotropic Hypogonadism Women

Background: To evaluate the outcomes of using in vitro fertilization (IVF)/ intracytoplasmic sperm injection (ICSI cycle) techniques in hypogonadotropic hypogonadism women and comparing them to women with tubal factor infertility. Materials and Methods: Data from 81 hypogonadotropic hypogonadism (HH) patients treated with IVF/ICSI in the period from early 2009 until the end of 2010 were analyzed and compared with treatment results from 89 patients with Tubal factor infertility. Moreover, data from hypogonadotropic hypogonadism patients were analyzed with respect to the age factor. P<0.05 was considered statistically significant. Results: Despite a higher fertilization rate and higher number of grade A/B embryos transferred in the Tubal factor group, the implantation, pregnancy and live birth rates were found to be similar between the two groups (p=0.3, p=0.1, p=0.6, respectively). When HH patients were evaluated according to the age factor, no significant difference was found regarding outcome parameters (p=0.2). Conclusion: HH women that were treated with IVF/ICSI cycles were found to have a good chance for pregnancy, even in coexistence with age factor.