Observation of Nocardia Asteroides Complex in a Patient with Corneal Ulceration: The First Case Report from Iran
نویسندگان
چکیده مقاله:
Background & Aims: Nocardia asteroides is gram-positive, partially acid-fast, aerobic actinomycetes which cause a wide range of skin infections, and pulmonary, cerebral, and ocular infection. Case Presentation: A 60-year-old man with diabetes presented with ocular ulcers in 2015. Through the medical records evaluation, physical examination, and biochemical evaluation of the patient, Nocardia asteroides complex was identified as the cause of infection. The patient was treated with amikacin and ciprofloxacin, and recovery was obtained and the patient was placed on the waiting list for corneal transplantation. Conclusion: Diagnosis of keratitis caused by Nocardia asteroides is difficult and it may be misdiagnosed due similarities with keratitis caused by nontuberculous mycobacteria (NTM). Therefore, suitable diagnosis methods and early diagnosis of ocular nocardiosis are necessary. In the present study, Nocardia asteroides complex was isolated from a corneal ulceration.
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Nocardia asteroides is a rare cause of keratitis usually associated with trauma. We report a case of corneal ulceration caused by N. asteroides in a patient with leprosy. This is the first case report of nocardial keratitis from Southeast Asia. The diminished corneal sensation in a patient with leprosy could be a predisposing factor for development or exacerbation of corneal ulceration.
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عنوان ژورنال
دوره 23 شماره 2
صفحات 228- 233
تاریخ انتشار 2016-03-01
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