O-33: Can Unilateral Ovariectomy Be Used asA Method of Infertility Treatment in Case ofResistant Polycystic Ovary Syndrome (ExperimentalResearch)
نویسنده
چکیده مقاله:
Background: Polycystic ovary syndrome (PCOS) is an endocrine disturbance that causes primary anovulation that result in infertility. There are more symptoms accompanying this syndrome: acne, hirsutism, obesity, irregular menstrual cycle and many others. This syndrome can be more or less successfully treated but in 10-15% of cases it is resistant to any kind of treatment used in nowadays practice.The aim of our research was to give a background to the usage of unilateral ovariectomy in reducing the severity of PCOS in case of resistant forms of this syndrome. Materials and Methods: Experiment was carried out on 72 Wistar female rats. 18 rats served as a control. We performed unilateral ovariectomy (UOE) on all of the rats from experimental group. Terms of observation were determined in 1, 3 and 6 month after the surgical intervention in order to compare the changes taking place in the ovary that was left. Results: It was revealed that in normal ovaries in 6 month after UOE the amount of growing and mature follicles is considerably decreased in comparison with the control group. In case of polycystic changed ovaries in 3 month after UOE it was revealed that partial restoration of the ovogenesis takes place. In 6 month after UOE performed on the ovaries with PCOS the formation of the yellow bodies was noted, which is not characteristic for this syndrome and tells about ovulation that took place in the ovary. Conclusion: Unilateral ovariectomy can be advised as the method of treatment of the resistant forms of polycystic ovary syndrome.
منابع مشابه
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عنوان ژورنال
دوره 4 شماره 2
صفحات -
تاریخ انتشار 2010-05-01
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