n-Octyl-3-methylpipyridinium bromide ([OMePPy]+Br-): novel ionic liquid to promote green synthesis of polycyclic fused acridines

In this research, various polycyclic fused acridines were synthesized via the highly efficient and green one-step four-component reaction between isatins, dimedone, various amines, and dimethylacetylenedicarboxylates (DMAD/DEAD) in the presence of n-octyl-3-methylpipyridinium bromide ([OMePPy]+Br-) as a newly prepared ionic liquid, in absolute green situations at room temperature under solvent-free conditions. The ionic liquid characterized by 1H NMR, 13C NMR, GC-MASS, TGA/ DTG, EDX, and FESEM techniques. Utilizing an eco-friendly and simply synthesized ionic liquid, green and economic reaction media, and preparing a wide range of polycyclic fused acridines in good yields are some highlighted aspects of the reported protocol.