Morphine and Angiogenesis in Hypertensive Animals
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منابع مشابه
Effects of Low-dose Morphine on Nitric Oxide Concentration and Angiogenesis in Two-kidney One Clip Hypertensive Rats
Objective(s) We investigated the effects of low-dose morphine on nitric oxide (NO) and angiogenesis in two-kidney one clip hypertensive (2K1C) rats. Materials and Methods Male rats were divided into two groups: sham-clip operated and 2K1C. Each group subdivided into saline and morphine (3 mg/kg i.p. 8 weeks) groups. Blood pressure, heart rate, plasma renin activity (PRA), NO concentration an...
متن کاملeffects of low-dose morphine on nitric oxide concentration and angiogenesis in two-kidney one clip hypertensive rats
objective(s) we investigated the effects of low-dose morphine on nitric oxide (no) and angiogenesis in two-kidney one clip hypertensive (2k1c) rats. materials and methods male rats were divided into two groups: sham-clip operated and 2k1c. each group subdivided into saline and morphine (3 mg/kg i.p. 8 weeks) groups. blood pressure, heart rate, plasma renin activity (pra), no concentration and m...
متن کاملLow Dose Morphine Enhances Morphine Antinociception Effects in the Animals Pretreated with Selective and Non-Selective Phosphodiestrase Inhibitors
In this study, we investigated the interactive effects of intraperitoneal (i.p.) injections of three different phosphodiesterase inhibitors (PDEIs) on morphine-induced analgesia in mice using tail-flick method. Subcutaneous administration of morphine (1, 3 and 6 mg/kg) caused significant antinociceptive effects in a dose dependent manner. Administration of pentoxifylline (12.5, 25, 50 an...
متن کاملEffects of Low-dose Morphine on Nitric Oxide Concentration and Angiogenesis in Two-kidney One Clip Hypertensive Rats
OBJECTIVES We investigated the effects of low-dose morphine on nitric oxide (NO) and angiogenesis in two-kidney one clip hypertensive (2K1C) rats. MATERIALS AND METHODS MALE RATS WERE DIVIDED INTO TWO GROUPS: sham-clip operated and 2K1C. Each group subdivided into saline and morphine (3 mg/kg i.p. 8 weeks) groups. Blood pressure, heart rate, plasma renin activity (PRA), NO concentration and m...
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عنوان ژورنال
دوره 15 شماره 2
صفحات 691- 692
تاریخ انتشار 2012-03-01
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