LAPAROSCOPIC OVARIAN DRILLING INCLOMIPHENE RESISTANT PCO PATIENTS: A PREFERRED METHOD OF TREATMENT

Objective: To determine the efficacy of ovarian drilling in PCO patients who failed to achieve pregnancy with medical treatment. Methods and Main Results: 75 patients with a diagnosis of PCO of whom 48(64%) were primary infertile and 27(36%) were secondary infertile were clomiphene resistant. The other methods like bromocriptin, gonadotropins, GnRH -a and metformin had been given to these patients for infertility treatment without benefit. After ovarian drilling, pregnancy was achieved in 41 patients (54.6%), 30(40%) in group I (primary infertile group) and 11 (14.6%) in group II (secondary infertile group). During the operation adhesiolysis was necessary in 14( 18.6%) and removal of endometriotic lesions was indicated in 5(6.6%) in both groups. Conclusion: Ovarian drilling is an ideal technique in PCO patients with failure of medical treatment, considering the benefit of also performing other necessary surgical interventions.