Interleukin-17 Gene Expression and Serum Levels in Children with Severe Asthma

interleukin-17 gene expression and serum levels in children with severe asthma

background: il-17 is a major cytokine player in t cell mediated leukocyte associated inflammation. il-17 is also recognized to participate in the pathophysiology of asthma. objective: to determine the role of il-17 in predicting severe asthma. methods: we obtained serum samples from asthmatic children under the age of 5-year in three different groups of mild (n=33), moderate (n=28) and severe (...

Interleukin-17 gene expression and serum levels in children with severe asthma.

BACKGROUND IL-17 is a major cytokine player in T cell mediated leukocyte associated inflammation. IL-17 is also recognized to participate in the pathophysiology of asthma. OBJECTIVE To determine the role of IL-17 in predicting severe asthma. METHODS We obtained serum samples from asthmatic children under the age of 5-year in three different groups of mild (n=33), moderate (n=28) and severe ...

Interleukin-17 Gene Expression and Serum Levels in Acute Rejected and non-Rejected Liver Transplant Patients

Background: Interleukin-17 (IL-17), as a potent proinflammatory cytokine, has a critical role in post liver transplant outcomes. However, there is not much information about the effects of IL-17 cytokine on acute liver rejection. Objective: To evaluate the role of IL-17 in post-liver transplant acute rejection. Methods: Ninety seven adult liver transplant patients who enrolled in this cross sec...

Interleukin-17 Serum Levels and TLR4 Polymorphisms in Ulcerative Colitis

Background: Inflammatory bowel disease, an autoimmune disease, has two clinical manifestations including Crohn’s disease and ulcerative colitis (UC). IL-17 has been the target of intensive research in autoimmune diseases. The influence of Toll like receptor 4 (TLR-4) gene polymorphisms on IL-17 production has also been revealed in UC patients and tissue inflammation in mice. Objectives: To inve...

interleukin-17 gene expression and serum levels in acute rejected and non-rejected liver transplant patients

background: interleukin-17 (il-17), as a potent proinflammatory cytokine, has a critical role in post liver transplant outcomes. however, there is not much information about the effects of il-17 cytokine on acute liver rejection. objective: to evaluate the role of il-17 in post-liver transplant acute rejection. methods: ninety seven adult liver transplant patients who enrolled in this cross sec...

Investigation of Interleukin-17 Gene Polymorphisms and Serum Levels in Patients with Basal Cell Carcinoma of the Skin