I-34: New Management Options for Ovarian Hyperstimulation Syndrome

Ovarian Hyperstimulation Syndrome (OHSS) is a rare complication of super ovulation and in vitro fertilization (IVF). Although our understanding of its pathophysiology is incomplete, induction of development of multiple follicles, perturbation of the renin angiotensin system and exposure to luteinizing hormone (LH) or human chorionic gonadotropin (hCG) are essential contributing factors to its development and offer unique opportunities for therapeutic intervention. Current therapeutic efforts are directed at identifying patients at risk, tailoring treatment to reduce risk of exuberant response, eliminating factors known to precipitate development of OHSS and utilizing treatments shown to reduce its development and Abstracts of the 12th Royan International Congress on Reproductive Biomedicine 1 7 International Journal of Fertility & Sterility (IJFS), Vol 5, Suppl 1, Summer 2011 hasten its resolution. This presentation highlights recent advances in its prevention, management and treatment with particular emphasis on use of cabergolide.