I-29: Luteal Phase Support in Frozen-Thawed Embryo Transfer Cycle

Cumulative pregnancy rate has been significantly increased since frozen-thawed embryo transfer was applied in ART cycles. This method has become an essential part of IVF/ICSI treatment. Luteal phase support has been proven to be associated with higher rate of live birth rate. Human chorionic gonadotropin (HCG), and progestrone have been successfully used for luteal phase support in ovarian stimulated ,fresh embryo transfer. Giving luteal phase support in frozen- thawed embryo transfer is still a debate. Since frozen-thawed embryo transfer is performed either in natural or pituitary suppressed cycle, it is important to determine the necessity of luteal phase support. For natural cycle in which ovulation is documented and corpus luteum exist, there is no physiological basis for luteal phase support.