Hypertrophic scars and Keloids
نویسندگان
چکیده مقاله:
The available treatment modalities for hypertrophic scars and keloids have very little success. Surgical treatment of these lesions without adjuvant therapy is also associated with high recurrence rate. Hypertrophic scars and keloids are the results of a series of cellular and molecular changes which their identification can guide us toward new treatment modalities which may decrease the pathological factors, or help balancing the repair mechanism; thus inhibiting extensive scar formation. In this article, we have reviewed the latest treatment methods, as well as molecular and cellular reactions, which lead to the formation of hypertrophic scars and keloids.
منابع مشابه
Management of keloids and hypertrophic scars.
Keloids and hypertrophic scars represent an exuberant healing response that poses a challenge for physicians. Patients at high risk of keloids are usually younger than 30 years and have darker skin. Sternal skin, shoulders and upper arms, earlobes, and cheeks are most susceptible to developing keloids and hypertrophic scars. High-risk trauma includes burns, ear piercing, and any factor that pro...
متن کاملTreatment of keloids and hypertrophic scars.
Clinicians always find it difficult to treat hypertrophic scars and keloids. Various treatment modalities are available. Intralesional corticosteroids, topical applications, cryotherapy, surgery, laser therapy, and silicone sheeting are the widely used options. Radiation therapy can also help in cases of recalcitrant keloids. Most recently, pulsed-dye laser has been successfully used to treat k...
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SUMMARY The development of cutaneous pathological scars, namely, hypertrophic scars (HSs) and keloids, involves complex pathways, and the exact mechanisms by which they are initiated, evolved, and regulated remain to be fully elucidated. The generally held concepts that keloids and HSs represent "aberrant wound healing" or that they are "characterized by hyalinized collagen bundles" have done l...
متن کاملManagement of keloids and hypertrophic scars: current and emerging options
In the context of growing aesthetic awareness, a rising number of patients feel disappointed with their scars and are frequently seeking help for functional and aesthetic improvement. However, excessive scarring following surgery or trauma remains difficult to improve despite a plethora of advocated treatment strategies as frequently observed in daily clinical routine. It is thus still preferab...
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عنوان ژورنال
دوره 6 شماره 3
صفحات 27- 34
تاریخ انتشار 2003-04-01
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