Hodgkin\'s Disease

The Hodgkins Fund Prizes

Viral-related RNA in Hodgkins' disease and other human lymphomas.

Molecular hybridization with radioactively labeled DNA complementary to the RNA of the Rauscher leukemia virus was used to probe for homologous RNA in human lymphomas. 22 of 32 specimens contained RNA possessing homology to the RNA of the mouse leukemia virus, but not to that of the unrelated viruses causing mammary tumors in mice or myeloblastosis in chickens. Normal adult and fetal tissues fa...

Motor neuron disease and its association with non-Hodgkins lymphoma.

M otor neuron disease (MND) is a neurodegenerative disorder characterized by muscle atrophy, brisk reflexes, spasticity, fasciculation, and atrophy. The onset of the disease is generally insidious. The pathological process may involve the motor cortex, the spinal cord, and the brainstem. 1 Only upper or only lower motor neurons may be affected. The disease may or may not be seen with neoplasms,...

Current strategies in the treatment of childhood Hodgkins disease.

Dramatic changes in the treatment of childhood Hodgkins disease have taken place during the past three decades. Contemporary combined modality treatment regimens produce durable disease-free survival in 90 to 100%of patients with early disease and in 70 to 85%of patients with advanced disease. Studies using chemotherapy alone also report high survival rates, and current studies are few to highl...

Non-Hodgkins Lymphoma presenting as Garcin’s Syndrome

An 80 year old man presented with a twelve month history of progressive multiple unilateral cranial nerve palsies. A gadolinium enhanced MRI scan of his head and neck was performed. This showed an extra-axial enhancing lesion, which enveloped the hemi-mandible at the level of the left inferior alveolar nerve, and a dumbbell shaped lesion within the cerebellopontine angle. An incisional biopsy w...

Hodgkins lymphoma with HIV infection.

The association between Hodgkins Lymphoma (HL) with HIV is common in adults but rare in children. A 5 year old boy, known case of HIV on antiretroviral therapy, presented with prolonged fever, multiple enlarged lymph nodes along with hepatosplenomegaly. A diagnosis of Hodgkins lymphoma was entertained on histopathological examination; further subtyping was done by immunohistochemistry.

Hodgkins lymphoma: treatment and prognosis

Supported in part by a grant provided by “IASIS” a non-profit organization raising funds for Research in Leukemias, Lymphomas and related disorders come. AAS I/IIA are definitely non-advanced for most study groups. Non-advanced stages are further classified as “early” or “early favourable” and “intermediate” or “early unfavourable” according to the presence of adverse features. Table 1 summariz...