Hemophagocytic lymphohistiocytosis secondary to T-cell Acute Lymphoblastic Leukemia with membranous tonsillitis

Hemophagocytic lymphohistiocytosis secondary to histoplasmosis

Diversity of T-cell receptor Gene Rearrangements in South Indian Patients with Common Acute Lymphoblastic Leukemia

Background: Precursor B-Acute Lymphoblastic Leukemia (precursor B-ALL) oc-curs due to the uncontrolled proliferation of B-lymphoid precursors arrested at a par-ticular stage of B-cell development. Precursor-B-ALL is classified mainly into pro-B-ALL, common-ALL and pre-B-ALL. The Common Acute Lymphoblastic Antigen CD10 is the marker for common-ALL. Objective: This study was aimed to examine the ...

Prolonged Vincristine Toxicity Induced by Concurrent Posaconazole in a Child with T-cell Acute Lymphoblastic Leukemia

Pregnancy-associated hemophagocytic lymphohistiocytosis secondary to NK/T cells lymphoma

RATIONALE Hemophagocytic lymphohistiocytosis (HLH) occurs primarily in pediatric population, or secondary to malignancy, infection, or autoimmune disease. This disease is rare and prognosis is generally poor. Only a small number of cases during pregnancy have been reported in literature. PATIENT CONCERNS We report a case of pregnancy-associated HLH secondary to natural killer (NK)/T cells lym...

Acute Liver Failure Secondary to Hemophagocytic Lymphohistiocytosis during Pregnancy

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation that mimics and occurs with other systemic diseases. A 35-year-old female presented with signs of viral illness at 13 weeks of pregnancy and progressed to acute liver failure (ALF). We discuss the diagnosis of HLH and Kikuchi-Fujimoto (KF) lymphadenitis in the context of pregnancy and ALF. HLH may respond to c...

Aggressive natural killer cell leukemia associated with hemophagocytic lymphohistiocytosis.

A 39-year-old man presented with fever, pancytopenia, hepatosplenomegaly, and hyperbilirubinemia, as well as elevated triglycerides, ferritin (.88 888 mg/L), and soluble interleukin-2 receptor (58 370 U/mL). The diagnostic criteria of hemophagocytic lymphohistiocytosis (HLH) were met. Bone marrow was empty, without hemophagocytosis. The patient received etoposide, dexamethasone, and rituximab b...