H2 Receptor Antagonists

Release of histamine by H2-receptor antagonists?

Effects of intracerebroventricular injection of histamine and H1, H2 receptor antagonists on electrocardiographic parameters in broiler chickens

The aim of this study was to assess the effects of exogenous histamine and H1 and H2 central receptorson electrocardiographic (ECG) parameters, heart rate and mean electrical axis in broiler chickens. For thispurpose, Ross broiler chickens (750-800 g weight) received intracerebroventricularly (ICV) histamine.Moreover, to determine the receptors involved in histamine-induced alterations in ECG c...

Metformin and vitamin B12 deficiency: the role of H2 receptor antagonists and proton pump inhibitors.

1. Bartram L et al. Survey of training in geriatric medicine in UK undergraduate medical schools. Age Ageing 2006; 35: 533–5. 2. Harden RM, Sowden S, Dunn WR. Some educational strategies in curriculum development. The SPICES model. Med Educ 1984; 18: 284–97. 3. Harden RM, Davis MH, Crosby JR. The new Dundee medical curriculum: a whole that is greater than the sum of the parts. Med Educ 1997; 31...

Effect of diet particle size and feeding of H2-receptor antagonists on gastric ulcers in swine.

Four experiments were conducted to evaluate the effect of diet and the administration of H2-antagonists in feed on gastric ulcer formation and performance of growing-finishing swine. Pigs receiving a finely ground diet (less than lmm) grew faster (.73 vs .68 kg/d, P less than .01) and had better feed utilization (3.47 vs 3.76, P less than .01) than pigs receiving a cracked corn-based diet. Inci...

[Single dose treatment with H2-receptor-antagonists: is bedtime administration too late?].

Using ambulatory ph-metry, intragastric acidity was measured over three separate 24 hour periods in each of 12 healthy volunteers receiving either (a) placebo (1800 h and 2200 h), (b) 300 mg ranitidine (1800 h) and placebo (2200 h), or (c) placebo (1800 h) and 300 mg ranitidine (2200 h). Ranitidine was significantly more effective in decreasing 24 h median intragastric acidity when the drug was...

Cost-effectiveness analysis: stress ulcer bleeding prophylaxis with proton pump inhibitors, H2 receptor antagonists.

OBJECTIVES Proton pump inhibitors (PPIs) and H2-receptor antagonists (H2RAs) present varying pharmacological efficacy in preventing stress ulcer bleeding (SUB) in intensive care units. The literature also reports disparate rates of ventilator-assisted pneumonia (VAP) as side effects of these treatments. We compared the cost-effectiveness of these two prophylactic pharmacological options. METH...