Glutamate ionotropic and metabotropic receptors affect feed intake in broiler cockerels

Ionotropic Glutamate Receptors and their Role in Neurological Diseases

Glutamate is extensively and relatively uniformly distributed in the central nervous system (CNS) and its effects mediated by two distinct groups of receptors including Ionotropic and metabotropic glutamate receptors. Concentration of glutamate in the nervous system is much higher than in other tissues. Glutamate receptors play an important role in synaptic transmission, neural plasticity and n...

Glutamate in the nucleus of the solitary tract activates both ionotropic and metabotropic glutamate receptors.

Glutamate is the proposed neurotransmitter of baroreceptor afferents at the level of the nucleus of the solitary tract (NTS). Blockade of ionotropic glutamate receptors with kynurenic acid blocks the arterial baroreflex but, paradoxically, does not abolish the response to exogenous glutamate. This study tested the hypothesis that exogenous glutamate in the NTS activates both ionotropic and meta...

Diet-induced thermogenesis and feed intake in poultry: broiler versus layer cockerels

Research with adult mammals has shown that the diet-induced thermogenesis (DIT) related to the oxidation of macronutrients has a negative feedback on feed intake (FI), depending on the nutrient considered: proteins are combusted first, then carbohydrates and finally fat, corresponding to their satiating ability. However, previous studies revealed no significant differences in DIT between broile...

Ligands for ionotropic glutamate receptors.

Marine-derived small molecules and peptides have played a central role in elaborating pharmacological specificities and neuronal functions of mammalian ionotropic glutamate receptors (iGluRs), the primary mediators of excitatory synaptic transmission in the central nervous system (CNS). As well, the pathological sequelae elicited by one class of compounds (the kainoids) constitute a widely-used...

Physiological evidence for ionotropic and metabotropic glutamate receptors in rat taste cells.

Monosodium glutamate (MSG) elicits a unique taste in humans called umami. Recent molecular studies suggest that glutamate receptors similar to those in brain are present in taste cells, but their precise role in taste transduction remains to be elucidated. We used giga-seal whole cell recording to examine the effects of MSG and glutamate receptor agonists on membrane properties of taste cells f...

Glutamate Receptors in Rat Taste Cells Physiological Evidence for Ionotropic and Metabotropic