Experimental study of interference between Pertussis antigens and Salk Poliomyelitis vaccine

experimental study of interference between pertussis antigens and salk poliomyelitis vaccine

an interference is observed between whooping-cough antigens and salk polioc vaccine even if the two components are mixed immediately before use. the phenomenon is more evident when flulid antigens are injected. pertussis soluble antigen, which gives a good serological response in rabbits, when used alone or combined with dt, is inactivated in the presence of salk polio vacc:ne

experimental study of interference between pertussis antigens and salk poliomyelitis vaccine

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The 1954 Salk poliomyelitis vaccine field trial.

Stability Study of Razi Trivalent and Monovalent Oral Poliomyelitis Vaccine

Stability studies play a critical role in assuring product quality at all points in the vaccine life cycle. These studies used to determine vaccine expiry date and vaccine efficacy. Accelerated stability and long term stability study performed for three batches of trivalent oral poliomyelitis vaccine (OPV) and three batches of monovalent OPV (type1) manufactured by Razi institute. After samplin...

TIIE BIGGEST PUBLIC IIEALTH EXPERIMENT EVER: The 1954 Field Trial of the Salk Poliomyelitis Vaccine

THE LARGEST and most expensive medical experiment in history was carried out in 1954. Well over a million young children participated, and the immediate direct costs were over 5 million dollars. The experiment was carried out to assess the effectiveness, if any, of the Salk vaccine as a protection against paralysis or death from poliomyelitis. The study was elaborate in many respects, most prom...

Poliomyelitis Vaccine

The Epidemiology of poliomgelitis has been investigated in our country Pasteur Institute; the incidence of Poliomgelitis, after the age of 4 years i's rare, in Iran.  Passive antibody of maternal origin do not interfere with production of active antibody after immunization.  Inactivated Polio Vaccine (salk) has been effective in reducing the incidence of poliomge­litis by approximately 90 per ...