Evaluation of immune status to measles in vaccinated population in Tehran, using enzyme-linked immunosorbent assay and the hemagglutination inhibition techniques

Abstract: Measles remains one of the leading causes of childhood morbidity and mortality in developing countries and is still a major public health concern in developed countries. Although live attenuated vaccine is used throughout the world, out breaks of disease still occur in many countries including Iran. Understanding measles outbreaks that occur after the initiation of measles elimination efforts will be critical in refining the strategies for measles elimination. The present study was performed to evaluate the immune status against measles after the mass campaign vaccination in 2003.In this study, Approximately 172 sera were analysed by ELISA and HI tests. The results indicated, 162 were positive (94.2%) and 10 were negative (5.8%) by HI test and 165 were positive (95.5%) and 7 were negative (4.1%) by the ELISA test.