Evaluation of Bactereuria and Antimicrobial Susceptibility among Hospitalized Patients With and Without Catheter in Kerman Province- Iran in 2011

Nearly 15% to 25% of patients in general hospitals have a catheter at some timeduring their stay. Up to 97% of nosocomial urinary tract infections (UTIs) are relatedto catheter. The type of bacteremia is usually polymicrobial which makes the treatmentmore difficult. Previous studies showed an increase in mortality from bacteremia in thesepatients. The aim of the present study was to compare the prevalence of UTIs amongpatients with and without catheter, and to detect the type of bacteriuria and antibacterialresistance pattern.In this cross sectional study, samples were taken between Jan 2011 and July 2011. 678hospitalized patients in different wards of Afzalipour hospital, Kerman- Iran, were enrolled inthe study. E-test was applied to detect the pattern of resistance to gentamicin, nitrofurantoin,ciprofloxacin, ceftriaxon and co-trimoxazole. Results showed positive culture samples in 86%of female patients.Escherichia coli, Candida and Staphylococcus aureus were detected in 72, 20 and 7 percentof the positive cultures, respectively. 52.3% of detected E.coli was sensitive to gentamicin , 62%to ceftriaxone, 71.4% to ciprofloxacin, and 91.9% were sensitive to nitrofurantoin. Therefore,the most sensitive antibiotics in UTIs were ciprofloxacin and ceftriaxone. Unfortunately, therate of antibacterial drug resistance was high in comparison with developed countries. Wiseselection of antibiotics at hospitals and increasing the knowledge of patients to prevent self useof antibiotics can reduce antimicrobial resistance.