Effect of Intratympanic Dexamethasone on Controlling Tinnitus and Hearing loss in Meniere’s Disease

Introduction: We investigated the effect of intratympanic dexamethasone on control of tinnitus and hearing loss in patients with Meniere’s disease.  Materials and Methods: 100 consecutive patients with a diagnosis of Meniere’s disease according to the 1995 criteria of The American Academy of Otolaryngology – Head and Neck Surgery (AAO–HNS) who remained symptomatic despite medical therapy were assigned to receive intratympanic dexamethasone. The results were assessed with respect to changes in hearing symptoms and tinnitus.  Results: Hearing improvement and improvement in SDS was observed in 52% and 35% of patients, respectively. Tinnitus score was improved in 57% of patients. There was no relationship between age, sex, duration of disease, unilaterality of disease, or response to therapy.  Conclusion:  Intratympanic dexamethasone may be effective in the symptomatic control of hearing loss and tinnitus in Meniere’s disease.