Does Intravenous or Intraarticular Tranexamic Acid (TXA) Reduce Joint Bleeding Following Arthroscopic Anterior Cruciate Ligament (ACL) Reconstruction and Arthroscopic Meniscectomy? Can Intraarticular Use be Harmful to Chondrocytes?

Arthroscopic knee surgery to perform partial meniscectomy and anterior cruciate ligament (ACL) reconstruction is frequent and effective, although a possible complication is postoperative intra-articular bleeding. When this complication occurs, in addition to the associated pain, the patient usually requires an arthrocentesis to avoid loss of joint mobility. Sometimes this problem ends up associated with a poor result of surgery due to loss of knee mobility. Therefore, recently, the use of tranaexamic acid (TXA) has been considered in order to reduce postoperative bleeding and its potential associated complications (1–3).