Diuretic Potential of Whole Plant Extracts of Pergularia daemia (Forsk.)
نویسندگان
چکیده مقاله:
The whole plant, Pergularia daemia (Family: Asclepediaceae), was extracted with 50% alcohol and a fresh batch of the plant material was successively extracted with petroleum ether, ethyl acetate and n-butanol to determine its diuretic activity. The diuretic activity of the different extracts at a dose of 400 mg/Kg was assessed orally in rats with furosemide as a standard drug using Lipschitzs test. All extracts except the petroleum ether extract showed significant increase (p < 0.001) in urine output. Urinary electrolyte excretion was also affected by the extracts: the alcoholic, ethyl acetate and n-butanol extract caused an increase in the urinary excretion of sodium and potassium ions. These findings suggest that among the mentioned extracts, ethanolic has the maximum diuretic activity followed by n-butanol extract.
منابع مشابه
diuretic potential of whole plant extracts of pergularia daemia (forsk.)
the whole plant, pergularia daemia (family: asclepediaceae), was extracted with 50% alcohol and a fresh batch of the plant material was successively extracted with petroleum ether, ethyl acetate and n-butanol to determine its diuretic activity. the diuretic activity of the different extracts at a dose of 400 mg/kg was assessed orally in rats with furosemide as a standard drug using lipschitzs t...
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عنوان ژورنال
دوره Volume 10 شماره 4
صفحات 795- 798
تاریخ انتشار 2011-12-12
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