Deep seated Candidiasis

[Molecular biology in the diagnosis of deep-seated candidiasis in the critically ill non-neutropenic patient].

Candida infections are an important cause of morbidity and mortality in critically ill patients. Rapid detection of the yeast in blood and other tissues by molecular biology methods has been the goal of some recent studies. An analysis of the sensitivity and specificity of these methods assayed in clinical specimens from critically ill and other patients is carried out. PCR amplification of rib...

Efficacy and tolerability of micafungin monotherapy for candidemia and deep-seated candidiasis in adults with cancer.

The response rate among 58 patients with cancer and candidemia or deep-seated candidiasis treated with micafungin monotherapy was 81%. Intensive care unit (ICU) stay, concomitant nonfungal infections, and acute kidney injury were significantly associated with the 30-day crude mortality rate. Severe neutropenia was an independent predictor of micafungin failure. The efficacy and safety of micafu...

Deep-seated sarcomas of the penis.

Mesenchymal neoplasias represent 5% of tumors affecting the penis. Due to the rarity of such tumors, there is no agreement concerning the best method for staging and managing these patients. Sarcomas of the penis can be classified as deep-seated if they derive from the structures forming the spongy body and the cavernous bodies. Superficial lesions are usually low-grade and show a small tendenc...

Deep seated infection due to Lactobacillus caseii.

The initial clinical diagnosis was one of infective endocarditis and treatment was started with parenteral ampicillin and gentamicin. One week after admission he remained unwell with an intermittent pyrexia. Computed tomographic scan (CT) demonstrated an enlarging, multi-loculated intra-abdominal abscess with subhepatic, peri-renal and peri-pancreatic collections. The sub-hepatic abscess was dr...

Deep-seated lipoma of the foot.

Deep-seated resistance in relapsed paratyphoid fever.

We describe a case of relapsed paratyphoid fever in which the isolate had reduced susceptibility to ciprofloxacin due to a rare mutation within the gyrA gene. 18fluorodeoxyglucose positron emission tomography scanning identified deep-seated infection including unsuspected aortitis and highlights the utility of novel imaging techniques to improve our understanding and treatment of this disease.