Curcumin Inhibits The Adverse Effects of Sodium Arsenite in Mouse Epididymal Sperm
نویسندگان
چکیده مقاله:
Objective The aim of this study was to investigate the effects of curcumin on epididymal sperm parameters in adult male Navel Medical Research Institute (NMRI) mice exposed to sodium arsenite. MaterialsAndMethods In this experimental study, we divided the animals into four groups: control, sodium arsenite (5 mg/kg), curcumin (100 mg/kg) and curcumin+sodium arsenite. Exposures were performed by intraperitoneal injections for a 5-week period. After the exposure period, we recorded the animals’ body and left testes weights. The left caudal epididymis was used to count the sperm number and analyze motility, viability, morphological abnormalities, acrosome reaction, DNA integrity, and histone-protamine replacement in the spermatozoa. One-way analysis of variance (ANOVA) followed by the Tukey’s test was used to assess the statistical significance of the data with SPSS 16.0. P
منابع مشابه
curcumin inhibits the adverse effects of sodium arsenite in mouse epididymal sperm
objective: the aim of this study was to investigate the effects of curcumin on epididymal sperm parameters in adult male navel medical research institute (nmri) mice exposed to sodium arsenite. materials and methods: in this experimental study, we divided the animals into four groups: control, sodium arsenite (5 mg/kg), curcumin (100 mg/kg) and curcumin+sodium arsenite. exposures were performed...
متن کاملCurcumin Inhibits The Adverse Effects of Sodium Arsenite in Mouse Epididymal Sperm
BACKGROUND The aim of this study was to investigate the effects of curcumin on epididy- mal sperm parameters in adult male Navel Medical Research Institute (NMRI) mice ex- posed to sodium arsenite. MATERIALS AND METHODS In this experimental study, we divided the animals into four groups: control, sodium arsenite (5 mg/kg), curcumin (100 mg/kg) and curcumin+sodium arsenite. Exposures were perf...
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عنوان ژورنال
دوره 10 شماره 2
صفحات 245- 252
تاریخ انتشار 2016-07-01
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