Comparing the Effect of Rosa damascena and Vinegar Mouthwash and Chlorhexidine Mouth Wash on Plaque-induced Gingivitis: A Single Blind Clinical Trial

Background and purpose: Gingivitis is a multifactorial disease caused by the interaction between pathogenic bacteria and different levels of host immune response. Plaque induced gingivitis is the most common form of gingivitis. There are some mechanical and chemical methods to attain plaque control. Due to the adverse effects of chlorhexidine, the aim of this study was to clinically compare the efficacy of Rosa damascena and vinegar mouthwash, and chlorhexidine on plaque induced gingivitis. Materials and methods: A double-blind randomized clinical trial was done in 112 individuals selected based on pilot data. The subjects were divided into three groups (2 case groups and 1 control group) and treated with chlorhexidine and Rosa damascena and vinegar mouthwash. Gingival index (GI), periodontal index (PI), and bleeding on probing (BOP) were recorded initially and later evaluated at weeks one and three. Data were analyzed by SPSS V20. Results: Reduction in PI, GI, and BOP was greater in chlorhexidine group followed by Rosa damascena and vinegar groups, while, the lowest rate of changes in the aforementioned indices was seen in placebo group. There were significant differences in BOP and GI between Rosa damascena and vinegar mouthwash and placebo (P<0.001). Conclusion: Rosa damascena and vinegar mouthwash are effective in treating gingivitis, but less effective than oral chlorhexidine mouthwash. Therefore, further longitudinal studies are needed to clarify the long term effect of Rosa damascena and vinegar mouthwash on gingivitis and other conditions such as periodontitis.   (Clinical Trials Registry Number: IRCT2017050233770N1)