Comparative study on the impact of low-dose ketamine with midazolam and with low-dose midazolam with ketamine to prevent shivering after spinal anesthesia

نویسندگان

چکیده مقاله:

Introduction: Shivering is one of the complications of spinal anesthesia. There are various methods to control this shivering. In this research we opted to study the effects of two different combination doses of ketamine and midazolam on the prevention of shivering after spinal anesthesia. Material and methods: Methods:The study was a double-blind clinical trial performed on 120 patients who were candidates for surgery under spinal anesthesia at Alzahra Hospital during 2017-2018. The patients were randomly allocated into 3 groups; A, B and C. Group A received 0.02 mg/kg low dose midazolam with 0.2 mg/kg ketamine. Group B received 0.04 mg/kg (regular dose) midazolam with 0.15 mg/kg low dose ketamine and group C received the same volume of normal saline as placebo before surgery. The demographic variables, intensity of shivering and the need for analgesic medications were assessed in the patients. Results: The mean blood pressure after intervention in group A was significantly lower than groups B and C. Furthermore, the intensity of shivering in group C was significantly higher that the other two groups (p<0.05. In addition, the recovery time needed for group B was significantly longer than groups A and C (p <0.05). Conclusion: Both combinations of midazolam and ketamine are effective in preventing shivering but it appeared that using low dose midazolam with ketamine is a more suitable combination than low dose ketamine with midazolam in terms of sustaining hemodynamic stability and a shorter recovery duration. 

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Low-dose ketamine with clonidine and midazolam for adult day care surgery.

EDITOR: The ideal anaesthetic for day-surgery procedures should give quick recovery without pain, nausea or vomiting and ensure a rapid return to preoperative mental state with rapid discharge and patient satisfaction. Ketamine was introduced into clinical practice nearly 40 yr ago but its use has declined. It nevertheless remains in regular use in certain surgical disciplines, e.g. paediatrics...

متن کامل

Prophylactic Low-Dose Ketamine to Prevent Post Anesthetic Shivering in Orthopedic Surgery: A Randomized-Controlled Study.

OBJECTIVE Post anesthetic shivering is one of the most common anesthesia complications. We compared the efficacy of low-dose ketamine with normal saline in preventing post anesthetic shivering in orthopedic surgery. MATERIAL AND METHOD The present study was a prospective, randomized, double-blind, controlled clinical trial involving 183 ASA I-II patients, aged 18 to 65 years whom underwent or...

متن کامل

Comparing low-dose intravenous ketamine-midazolam with intravenous morphine with respect to pain control in patients with closed limb fracture

BACKGROUND We assessed the effects of low-dose IV ketamine-midazolam versus morphine on pain control in patients with closed limb fracture(s); and also compared the incidence of adverse events (cardio-pulmonary) between two groups. MATERIALS AND METHODS This prospective, single-blind, non-inferiority trial randomized consecutive emergency department (ED) patients aged 18-60 years to two group...

متن کامل

Comments on "The Effect of Low-dose Ketamine on Post-caesarean Delivery Analgesia after Spinal Anesthesia"

Received September 24, 2013. Accepted October 8, 2013. Correspondence to: Mohamed Amin Ghobadifar Department of Student Research Committee, Medicine School, Jahrom University of Medical Sciences, Motahari Avenue, Jahrom, Iran Tel: +98-917-1020-790, Fax: +98-711-635-40-94, E-mail: [email protected] This is an open-access article distributed under the terms of the Creative Commons Attribution N...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 24  شماره 5

صفحات  0- 0

تاریخ انتشار 2019-11

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

کلمات کلیدی

کلمات کلیدی برای این مقاله ارائه نشده است

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023