Colorimetric gold nanoparticles-based aptasensors

Aptamer-based colorimetric biosensing of abrin using catalytic gold nanoparticles.

In this study we propose a simple and sensitive colorimetric aptasensor for the quantitative analysis of abrin by using catalytic AuNPs for the first time. AuNPs possess the peroxidase-like activity that can catalyse 3,3,5,5-tetramethylbenzidine (TMB) in the presence of H2O2, leading to color change of the solution. It is interesting to find that the peroxidase-like activity of AuNPs can be imp...

Paper-based tuberculosis diagnostic devices with colorimetric gold nanoparticles

A colorimetric sensing strategy employing gold nanoparticles and a paper assay platform has been developed for tuberculosis diagnosis. Unmodified gold nanoparticles and single-stranded detection oligonucleotides are used to achieve rapid diagnosis without complicated and time-consuming thiolated or other surface-modified probe preparation processes. To eliminate the use of sophisticated equipme...

Colorimetric biosensing of pathogens using gold nanoparticles.

Rapid detection of pathogens is crucial to minimize adverse health impacts of nosocomial, foodborne, and waterborne diseases. Gold nanoparticles are extremely successful at detecting pathogens due to their ability to provide a simple and rapid color change when their environment is altered. Here, we review general strategies of implementing gold nanoparticles in colorimetric biosensors. First, ...

Colorimetric Identification of Proteins Using Gold Nanoparticles

Colorimetric Aptasensor Using Unmodified Gold Nanoparticles for Homogeneous Multiplex Detection

Colorimetric aptasensors using unmodified gold nanoparticles (AuNPs) have attracted much attention because of their low cost, simplicity, and practicality, and they have been developed for various targets in the past several years. However, previous research has focused on developing single-target assays. Here, we report the development of a homogeneous multiplex aptasensor by using more than o...

Colorimetric recognition of DNA intercalators with unmodified gold nanoparticles.

A colorimetric approach to recognize the binding mode between DNA and molecules was developed, which was based upon the electrostatic interaction between DNA and gold colloids.