Carob (Ceratonia siliqua L.) fruit hydro-alcoholic extract alleviates reproductive toxicity of lead in male mice: Evidence on sperm parameters, sex hormones, oxidative stress biomarkers and expression of Nrf2 and iNOS

Effect of Carob (Ceratonia siliqua L.) oral supplementation on changes of semen parameters, oxidative stress, inflammatory biomarkers and reproductive hormones in infertile men

Background and Aim: Reduction in sperm motility is one of the main causes of male infertility. The aim of this study was to investigate the effect of Carob supplementation on sperm parameters, inflammatory factors, oxidative stress indices and sex hormones in the men with idiopathic infertility. Materials and Methods: This study was a randomized double-blind controlled clinical trial which inc...

Effect of Ceratonia siliqua (Carob) syrup and vitamin E on sperm parameters, oxidative stress index and sex hormones in infertile men: Protocol for a randomized controlled trial

Background: Spermatogenesis is a necessary process in fertility and reproductive capacity of humans. In view of the relative high prevalence of spermatogenesis disorders in men and the failure of treatments provided in conventional medicine, new therapeutic approaches are being considered. This study will be designed to investigate the effect of Ceratonia siliqua (Carob) syrup and vitamin E on ...

Gastroprotective effect of carob (Ceratonia siliqua L.) against ethanol-induced oxidative stress in rat

BACKGROUND We aimed in the present study, at investigating the gastroprotective effect of carob pods aqueous extract (CPAE) against ethanol-induced oxidative stress in rats as well as the mechanism implicated. METHODS Adult male wistar rats were used and divided into six groups of ten each: control, EtOH (80% v/v, 4 g/kg b.w.), EtOH 80% + various doses of CPAE (500, 1000 and 2000 mg/kg, b.w.)...

Clonal Propagation of Carob (ceratonia Siliqua L., Fabaceae)

Mature seeds of carob tree (Ceratonia siliqua L.) were germinated on hormone free MS medium. Efforts were made to develop multiple shoots by using axillary buds of in vitro grown seedlings on MS medium fortified with different concentrations of BA singly and BA in combination with IAA or GA3. Axillary buds produced single shoot with a moderate amount of callus at the base of the explant after c...

Effects of salinity and drought stress on growth and echophysiolgical parameters in carob tree seedlings (Ceratonia siliqua L.)

Lipid Profiling of the Carob Fruit (Ceratonia Siliqua L.) Using GC/LC/QTOF Accurate Mass Spectrometry

The carob tree (Ceratonia siliqua L.) is a native of the Mediterranean basin with several applications in the food, textile and cosmetics industries [1]. It belongs to the Caesalpinaceae sub-family of the family Leguminoseae [2].The pods of the carob fruit have long been used as a feed for livestock and in human nutrition, including sweets, biscuits and processed drinks, because of its high sug...