Bone scintigraphy in diagnosing chronic recurrent multifocal osteomyelitis
نویسندگان
چکیده مقاله:
A 10-year-old boy was referred to us for evaluation of FUO accompanied with bone pain in both calves. Three hours after intravenous injection of 13 mCi of 99mTc-MDP, whole body scan in multiple spot views was performed. The scan showed symmetrical areas of diffusely increased tracer uptake in multiple long bones. Histopathologic evaluation confirmed osteosclrosis and fibrotic changes without any bacterial growth in the specimen culture. Based on patient’s history, lab results, bone scan and histopathologic findings, chronic recurrent multifocal osteomyelitis (CRMO) was considered as the most likely diagnosis. Dramatic response to NSAIDs and pamidronate therapy confirmed the diagnosis of CRMO.
منابع مشابه
bone scintigraphy in diagnosing chronic recurrent multifocal osteomyelitis
a 10-year-old boy was referred to us for evaluation of fuo accompanied with bone pain in both calves. three hours after intravenous injection of 13 mci of 99mtc-mdp, whole body scan in multiple spot views was performed. the scan showed symmetrical areas of diffusely increased tracer uptake in multiple long bones. histopathologic evaluation confirmed osteosclrosis and fibrotic changes without an...
متن کاملChronic Recurrent Multifocal Osteomyelitis in a 9-year-old Boy
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare aseptic, auto-inflammatory bone disorder. CRMO presents with bone pain with or without fever. The diagnosis of CRMO is a diagnosis of exclusion and should be included in the differential diagnosis of chronic inflammatory bone lesions in children. Cultures of the bone are typically sterile, antibiotic therapy does not result in clinic...
متن کاملChronic recurrent multifocal osteomyelitis.
Chronic recurrent multifocal osteomyelitis is an autoinflammatory disorder characterized by bone pain and fever, a course of exacerbations and remissions, and a frequent association with other inflammatory conditions. Because its etiology is largely unknown, the diagnosis is still based on clinical criteria; treatment is empiric and not always successful. The diagnosis is supported by the prese...
متن کاملChronic recurrent multifocal osteomyelitis; manifestation, imaging and diagnosis
Chronic recurrent multifocal osteomyelitis (CRMO) is an inflammatory bone disease usually affecting children. A 9-year old boy presented with recurrent lower extremities pain and discomfort lasting for two years. In every time, symptoms vanished after several weeks. The patient received antibiotics only in one period of bone pain. In other occasions the patient didn’t received any antibiotics. ...
متن کاملPaediatric chronic recurrent multifocal osteomyelitis.
To cite: Wong DR, Wong GR, Moussa B, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2016-218957 DESCRIPTION A previously healthy girl aged 15 years presented with a 3-month history of low back pain, lethargy, morning stiffness and nocturnal back discomfort. She had no significant history of weight loss, infective symptoms or neurological symptoms, includi...
متن کامل[Chronic recurrent multifocal osteomyelitis in children].
We have studied retrospectively a series of 10 children presenting with chronic multifocal osteomyelitis (8 girls, 2 boys, 7 to 16 years). All patients had plain films, bone scintigraphies and histological studies. Three had CT scan and/or MRI. compared with literature data, we observed only one case of palmoplantar pustulosis and only 2 cases of lysis of the medial extremity of the clavicle; i...
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عنوان ژورنال
دوره 25 شماره Supplement 1
صفحات 66- 69
تاریخ انتشار 2017-02-01
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