Bone regeneration in dentistry using bioactive glass 49S :A review

Background and Aim: The aim of this study was to evaluate the effect of 49S bioactive glass nanoparticles made by sol-gel technique on bone regeneration in dentistry. These glass are especially used as bone repair materials because of their properties such as biodegradability and bioactivity, so they seem to be successful in orthopedic and dental surgery. Material and Methods: Acoording to this review, articles were searched using the keywords in Science direct, Google Scholar, PubMed, and Silivica databases between year 2006-2018, and 35 most related articles were choose. Results: According to studies, bioactive glass can perform specific biological activities after implantation. Due to the amount of ions released by the dissolution of these nano materials, they can be used for bone repair and dental problems. Conclusions: The bioactive glass 49S is preferred over other materials because of its special propertie Such as having nano-sized particles, the ability to bind to the soft tissue, ions release that influences bone growth and proliferation and differentiation of bone marrow cells. It is therefore suitable alternative to the orthopedic and dental bone grafts.