Bone marrow and cervical lymph nodes metastases as prodromal manifestations of malignant melanoma in a child

نویسندگان

  • Alireza Jenabzadeh Department of pediatric oncology, Shahid Sadoughi University of Medical Sciences, Yazd,Iran
  • Fariba Binesh Department of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd,Iran
  • Fatemeh PourHosseini Department of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd,Iran
  • Hadi Zare-Zardini Hematology and oncology research center, Shahid Sadoughi University of Medical Sciences, Yazd,Iran
  • Maryam Vagihinejad Department of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd,Iran
  • Mohammad Ali Dideban Department of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd,Iran
چکیده مقاله:

Malignant melanoma in children is rare. It can arise from congenital melanocytic nevi. In pediatric patients, diagnosis of melanoma is difficult and challenging because the physicians have a low index of suspicion. Marrow metastasis in malignant melanoma especially in children is extremely uncommon. Here, the authors reported a 5 year old girl who was presented with a 4 month history of pelvic and right lower limb pain and limping to the pediatric outpatient clinic in August 2016  at Shahid sadoughi Hospital,Yazd,Iran. She was febrile and had right cervical lymphadenopathy and scalp congenital nevus. The investigations confirmed the diagnosis of malignant melanoma with marrow and cervical lymph node metastases. The patient underwent multidisciplinary management and she was followed up closely. Metastatic malignant melanoma is a rare and dangerous disease with poor prognosis in children. It should be considered in differential diagnosis of children with congenital melanocytic nevi.

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عنوان ژورنال

دوره 8  شماره 1

صفحات  71- 74

تاریخ انتشار 2018-01

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