Apoptotic and proliferative activity of mouse gastric mucosa following oral administration of fumonisin B1
نویسندگان
چکیده مقاله:
Objective(s):Fumonisins are a group of toxic and carcinogenic mycotoxins, which contaminate the grains and their products. The aim of this study was to examine the apoptotic and proliferative activity of mouse gastric mucosa following administration of fumonisin B1 (FB1). Materials and Methods: Twenty-nine female mice divided into treatment (n=15) and control (n=14) groups. The treatment group received FB1 (150 mg/kg diet) for 16 weeks. The gastric atrophy was allocated using grading criteria modeled on the updated Sydney System. Immunohistochemistry studies were performed for evaluation of apoptosis and proliferative activity in gastric mucosa. Results: Mild to moderate gastric atrophy were observed in microscopic findings of the gastric mucosa in treated animals (P
منابع مشابه
apoptotic and proliferative activity of mouse gastric mucosa following oral administration of fumonisin b1
objective(s):fumonisins are a group of toxic and carcinogenic mycotoxins, which contaminate the grains and their products. the aim of this study was to examine the apoptotic and proliferative activity of mouse gastric mucosa following administration of fumonisin b1 (fb1). materials and methods: twenty-nine female mice divided into treatment (n=15) and control (n=14) groups. the treatment gro...
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عنوان ژورنال
دوره 18 شماره 1
صفحات 8- 13
تاریخ انتشار 2015-01-01
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