Analyses of methylation status of CpG islands in promoters of miR-9 genes family in human gastric adenocarcinoma

analyses of methylation status of cpg islands in promoters of mir-9 genes family in human gastric adenocarcinoma

in the recent years deregulation for micrornas expression pattern have emerged as a possible molecular factor for carcinogenesis. it has been reported that the expression of mir-9 was down-regulated in human gastric adenocarcinoma. to figure out the molecular mechanism of this down regulation, the methylation status in promoters of mir-9 family loci were compared in the human gastric adenocarci...

on the status of mixed methods research in applied linguistics

چکیده ندارد.

Performance of methylation and expression fluctuations of sonic hedgehog genes in gastric adenocarcinoma

Gastric cancer (GC) is considered as one of the most serious cancers, and in Iran, due to environmental factors in different regions, it has a high frequency. Apart from environmental factors, genetic and epigenetic ones also play a key role in the development of carcinogenesis of GC. In this regard, the study of functioning of the molecular mechanisms involved in the carcinogenesis and also tu...

Predicting methylation status of CpG islands in the human brain

MOTIVATION Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulation. Mis-epigenetic silencing associated with aberrant CpG island methylation is one mechanism leading to the loss of tumor suppressor functions in cancer cells. Large-scale experimental detection of DNA methylation is still b...

Methylation Status of CpG Islands Flanking