ALLOGENIC BONE MARROW TRANSPLANTATION IN APLASTIC ANEMIA
نویسندگان
چکیده مقاله:
Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respectively. Eleven patients are alive (61 %) and seven (39%) died. Twelve patients developed acute GVHD. We found an inverse relationship between the incidence of acute GVHD and the number of units of transfused packed cells and platelets before BMT (p 1000, PLT> 100000) after BMT was inversely related to the total number of cells transplanted (p<0.05).
منابع مشابه
allogenic bone marrow transplantation in aplastic anemia
eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (bmt) from hla-matched siblings during the period of 1990 to 1996. the conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. antilymphocyte globulin (alg) and cyclosporine were used for rejection and acute gvhd prophylaxis, respective...
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عنوان ژورنال
دوره 12 شماره 3
صفحات 217- 220
تاریخ انتشار 1998-11
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