A Simulation Study on Patient Setup Errors in External Beam Radiotherapy Using an Anthropomorphic 4D Phantom

نویسندگان

  • Ahmad Esmaili Torshabi Department of Electrical and Computer Engineering, Medical Radiation Group, Graduate University of Advanced Technology, Haft Bagh Highway, Knowledge Paradise, Kerman, Iran.
  • Mohammad Reza Rezaie Department of Electrical and Computer Engineering, Medical Radiation Group, Graduate University of Advanced Technology, Haft Bagh Highway, Knowledge Paradise, Kerman, Iran.
  • Payam Samadi Miandoab Department of Electrical and Computer Engineering, Medical Radiation Group, Graduate University of Advanced Technology, Haft Bagh Highway, Knowledge Paradise, Kerman, Iran.
  • Saber Nankali Department of Electrical and Computer Engineering, Medical Radiation Group, Graduate University of Advanced Technology, Haft Bagh Highway, Knowledge Paradise, Kerman, Iran.
چکیده مقاله:

Introduction Patient set-up optimization is required in radiotherapy to fill the accuracy gap between personalized treatment planning and uncertainties in the irradiation set-up. In this study, we aimed to develop a new method based on neural network to estimate patient geometrical setup using 4-dimensional (4D) XCAT anthropomorphic phantom. Materials and Methods To access 4D modeling of motion of dynamic organs, a phantom employs non-uniform rational B-splines (NURBS)-based Cardiac-Torso method with spline-based model to generate 4D computed tomography (CT) images. First, to generate all the possible roto-translation positions, the 4D CT images were imported to Medical Image Data Examiner (AMIDE). Then, for automatic, real time verification of geometrical setup, an artificial neural network (ANN) was proposed to estimate patient displacement, using training sets. Moreover, three external motion markers were synchronized with a patient couch position as reference points. In addition, the technique was validated through simulated activities by using reference 4D CT data acquired from five patients. Results The results indicated that patient geometrical set-up is highly depended on the comprehensiveness of training set. By using ANN model, the average patient setup error in XCAT phantom was reduced from 17.26 mm to 0.50 mm. In addition, in the five real patients, these average errors were decreased from 18.26 mm to 1.48 mm various breathing phases ranging from inhalation to exhalation were taken into account for patient setup. Uncertainty error assessment and different setup errors were obtained from each respiration phase. Conclusion This study proposed a new method for alignment of patient setup error using ANN model. Additionally, our correlation model (ANN) could estimate true patient position with less error.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

a simulation study on patient setup errors in external beam radiotherapy using an anthropomorphic 4d phantom

introduction patient set-up optimization is required in radiotherapy to fill the accuracy gap between personalized treatment planning and uncertainties in the irradiation set-up. in this study, we aimed to develop a new method based on neural network to estimate patient geometrical setup using 4-dimensional (4d) xcat anthropomorphic phantom. materials and methods to access 4d modeling of motion...

متن کامل

Evaluation of a 4D Cone-Beam CT Reconstruction Approach Using an Anthropomorphic Phantom

We have previously developed image-guided navigation systems for thoracic abdominal interventions utilizing a three dimensional (3D) Cone-Beam CT (CBCT) image acquired at breath-hold. These systems required the physician to perform the intervention in a gated manner, with actions performed at the same respiratory phase in which the CBCT image was acquired. This approach is not always applicable...

متن کامل

An Analysis of Setup Errors Using OnBoard Imager Technique in External Beam Radiotherapy for Different Cases in Radiation Oncology

Successful delivery of conformal fields requires stringent immobilization and treatment verification, as well as knowledge of the setup reproducibility. [1] Before coming OBI, electronic portal imaging detector was used to detect the setup errors. EPID images are not clear vision to identify correctly and immediately because they were produced by megavoltage X-ray during treatment setup. In OBI...

متن کامل

a study on rate making and required reserves determination in reinsurance market: a simulation

reinsurance is widely recognized as an important instrument in the capital management of an insurance company as well as its risk management tool. this thesis is intended to determine premium rates for different types of reinsurance policies. also, given the fact that the reinsurance coverage of every company depends upon its reserves, so different types of reserves and the method of their calc...

Estimation of the thyroid secondary cancer risk on the patient of standard breast external beam radiotherapy

Introduction: The purpose of this study was to estimate the secondary cancer risk of thyroid for standard radiotherapy methods which are commonly used for breast cancer patients. Materials and Methods: Sixty-four breast cancer patients (their age range was around 50 years old) who referred to Seyed- Al- Shohada hospital (Isfahan, Iran) were included in this ...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 13  شماره 4

صفحات  276- 288

تاریخ انتشار 2016-12-01

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023