A case of Shy, Drager Syndrome

[Shy-Drager syndrome].

Shy-Drager syndrome: a case report with polysomnography.

The authors report a case of Shy-Drager syndrome in a 53 year-old male patient. Autonomic failure was made evident by physical examination as well as laboratory tests. A sleep recording showed decreased percentage of REM sleep and apneas of the central type. The possible mechanisms for this sleep disorder are discussed.

Parkisonism with Shy-Drager syndrome--a case report.

A previously healthy 60 years old female patient presented with bradykinesia, postural instability and increased rigidity of both upper and lower limbs for 2 years and was diagnosed as Parkinsonism for last years. Later on she developed features of autonomic dysfunction including postural hypotension, hyperhydrosis and urinary incontinence so was diagnosed as Shy-Drager Syndrome. She was treate...

Effect of xamoterol in Shy-Drager syndrome.

BACKGROUND Xamoterol, a cardioselective beta 1-adrenoceptor partial agonist, has been reported to be effective on postural hypotension. We investigated the effect of xamoterol in five patients with Shy-Drager syndrome (SDS) in relation to their prevailing sympathetic nerve activity and sensitivity of beta-adrenoceptors and the change in circadian variation of blood pressure. METHODS AND RESUL...

Shy-Drager syndrome: recognition and management.

Shy-Drager syndrome is an uncommon disorder in which the patient experiences progressive autonomic failure. It is a multisystem degenerative disease that involves the central autonomic, cerebellar, basal ganglia, pyramidal, or spinal motor neurons. The mean age of onset is 55 years. A male predominance is noted, with a 2 or 3:1 ratio. About 11 percent of patients with orthostatic hypotension ha...

Speech symptoms associated with early signs of Shy Drager syndrome.

Speech disturbances reflecting impaired laryngeal control were found in ten patients whose autonomic dysfunction was associated with central neurological disease (Shy Drager Syndrome). In contrast, ten patients with progressive autonomic failure without evidence of CNS involvement had no difficulties on speech function tasks in comparison with normal controls. Presence of speech symptoms may ai...