Yellow Fever Vaccination: An Issue for Non-endemic Tropical Countries
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Yellow fever as an endemic/epidemic disease and priorities for vaccination.
Yellow fever is a potentially fatal viral hemorrhagic fever. Although an effective vaccine (yellow fever 17D) has been available since the late 1930s, utilization is incomplete in many areas, particularly in Africa, with the result that yellow fever epidemics still occur. Official reports of yellow fever between 1965 and 2004 in South America and Africa total over 33,000 cases. In West Africa, ...
full textYellow Fever Vaccination Essential for Angola, Who Reminds Travellers
Since the outbreak in Angola began in December 2015, 1975 suspected cases of yellow fever (618 laboratory confirmed) and 258 deaths have been reported, the majority of them in the capital, Luanda, and in two other provinces. Amid concerns that the virus will spread to other urban areas and to neighbouring countries, a large-scale vaccination campaign was launched in February 2016 and has so far...
full textYellow fever: an update.
Yellow fever, the original viral haemorrhagic fever, was one of the most feared lethal diseases before the development of an effective vaccine. Today the disease still affects as many as 200,000 persons annually in tropical regions of Africa and South America, and poses a significant hazard to unvaccinated travellers to these areas. Yellow fever is transmitted in a cycle involving monkeys and m...
full textDissection of Antibody Specificities Induced by Yellow Fever Vaccination
The live attenuated yellow fever (YF) vaccine has an excellent record of efficacy and one dose provides long-lasting immunity, which in many cases may last a lifetime. Vaccination stimulates strong innate and adaptive immune responses, and neutralizing antibodies are considered to be the major effectors that correlate with protection from disease. Similar to other flaviviruses, such antibodies ...
full textEquilibrium Analysis of a Yellow Fever Dynamical Model with Vaccination
We propose an equilibrium analysis of a dynamical model of yellow fever transmission in the presence of a vaccine. The model considers both human and vector populations. We found thresholds parameters that affect the development of the disease and the infectious status of the human population in the presence of a vaccine whose protection may wane over time. In particular, we derived a threshold...
full textDuration of post-vaccination immunity against yellow fever in adults.
INTRODUCTION Available scientific evidence to recommend or to advise against booster doses of yellow fever vaccine (YFV) is inconclusive. A study to estimate the seropositivity rate and geometric mean titres (GMT) of adults with varied times of vaccination was aimed to provide elements to revise the need and the timing of revaccination. METHODS Adults from the cities of Rio de Janeiro and Alf...
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volume 6 issue 2
pages 86- 87
publication date 2017-11-15
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