Y Choromosomal Microdeletion Screening in The Workup of Male Infertility and Its Current Status in India
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y choromosomal microdeletion screening in the workup of male infertility and its current status in india
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full textY Choromosomal Microdeletion Screening in The Workup of Male Infertility and Its Current Status in India
Spermatogenesis is an essential stage in human male gamete development, which is regulated by many Y chromosome specific genes. Most of these genes are centred in a specific region located on the long arm of the human Y chromosome known as the azoospermia factor region (AZF). Deletion events are common in Y chromosome because of its peculiar structural organization. Astonishingly, among the sev...
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15 صفحه اولCorrelation between Y chromosome microdeletion and male infertility.
Dyszoospermia due to genetic factors is the leading cause of male infertility. To explore the correlation between azoospermia factor (AZF) microdeletion of the Y chromosome and male infertility, we evaluated AZF microdeletion on the long arm of the Y chromosome in 166 infertile males and 50 fertile males using multiplex polymerase chain reactions amplification and gel electrophoresis. The resul...
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volume 7 issue 4
pages 253- 266
publication date 2014-12-01
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