Xylazine-Lidocain Combination for Retrobulbar Block in Goats

Objective- This  study  was  performed  to  investigate  the  analgesic  effects  of  lidocaine, xylazine and lidocaine/xylazine combination in eye regional anesthesia. Design- Experimental Study. Animals- Twenty adult goats were randomly designed in 4 groups. Procedures- In group L: 10 ml mixture of lidocaine 2% (5 mg/kg bw) and normal saline, In group LX: 10 ml mixture of lidocaine 2% (5 mg/kg bw), xylazine 2% (0.05 mg/kg bw) and normal saline, In group X: 10 ml mixture of xylazine 2% (0.05 mg/kg bw) and normal saline and In group C: 10 ml of normal saline were injected into the retrobulbar space of left eyes via  four point method. Onset  and duration of  eyelids  analgesia  and glob  analgesia/akinesia were compared between the groups. The  images were  studied  serially  and  compared  anatomically with  two  dissected  head  and intact goat skulls. Results- The  results of  this  study demonstrated  that  eye  regional  anesthesia have not been observed in group C. In group X, sedative effect of xylazine without complete loss of eyelids and glob  anaesthesia was observed. There was no  significant difference  in onset of  eyelids and glob anaesthesia between groups L and LX (p>0.05). Duration of eye regional anesthesia in group LX was significantly more than group L (p<0.05). The animals in groups X and LX were sedated during the study but in group L the animals were alert and nervous. Conclusion  and  Clinical  Relevance- According  to  results  of  present study,  addition  of xylazine to lidocaine for retrobulbar block causes a sedative effect and increased duration of eye regional anesthesia.