Unusual Presentation of the Rathke Cleft Cyst: A 25-Year-Old Female

Introduction: Rathke cleft cysts (RCC’s) are cystic sellar and supra sellar benign lesions which are thought to originate from the remnants of Rathke’s pouch. There are no specific clinical or radiological signs to differentiate them from other pituitary lesions. Presentation of Case: We report a 25-year-old female presented with hyperandrogenism and menstrual disorder, with the preliminary diagnosis of pituitary adenoma, based on clinic or radiologic features. The patient underwent endoscopic trans-sphenoid surgery, with the final histopathologic diagnosis of   Rathke cleft cyst. Discussion: Rathke cleft cysts (RCC) are generally asymptomatic, and the most common clinical findings are headache, pituitary dysfunction and visual disturbances It is important to diagnose the patient's problem at an early stage, based on the history, hormone profile, laboratory and radiologic findings. Conclusion: The presented case highlights the challenging pre-operative diagnosis of Rathke’s cyst.