Tongue Squamous Cell Carcinoma: A Clinical Study

Authors

  • Amin Rahpeyma Oral and Maxillofacial Diseases Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
  • Hamidreza Azimi Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
  • Saeedeh Khajehahmadi Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract:

  Background and Objectives: Squamous cell carcinoma of the tongue (SCCOT) is the most common malignant neoplasm in oral cavity. At the time of the diagnosis of SCCOT regional metastases with a high mortality rate are common, which is due to the extensive lymphatic system drainage of the tongue. Although the level of healthcare has significantly improved, the survival rate is still low with an unsatisfactory cure rate. The present study was designed to establish a clinical review on adults with SCCOT and to determine whether the rate of SCCOT has been changed over the 20-year. Methods: A cohort of 102 patients was recruited for this retrospective study. The study was carried out by reviewing the medical reports and case notes of patients with histologically confirmed SCCOT. Results: The peak incidence was observed between 60 and 70 years. Stage I disease was found in 24, stage II in 64, stage III in 10 and stage IV in four patients. Seventy-three patients were treated with combined therapy; surgery and radiation, whereas, 29 patients received only surgery. The overall 5-year survival was 60%. Thirty patients developed tumor recurrence including 12 local, 12 nodal, four locoregional, and two distant. Thirty-four patients died during the follow-up period, six with persistent disease, and 62 remained cancer free, giving a mortality and morbidity rate of 39%. Conclusion: This study recommends aggressive early treatment of patients with SCCOT including resection of the primary tumor with a safe margin (1.5cm) in addition to an appropriate neck dissection.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

tongue squamous cell carcinoma: a clinical study

background and objectives: squamous cell carcinoma of the tongue (sccot) is the most common malignant neoplasm in oral cavity. at the time of the diagnosis of sccot regional metastases with a high mortality rate are common, which is due to the extensive lymphatic system drainage of the tongue. although the level of healthcare has significantly improved, the survival rate is still low with an un...

full text

Coexistence of Granular Cell Tumor with Squamous Cell Carcinoma on the Tongue: A Case Report

Introduction: Granular cell tumors (GCTs) are rare and mostly benign soft tissue tumors. Though they have been reported in all parts of body, they are generally located in the head and neck region, especially on the tongue. Some malign forms exist, but these have been rarely reported. Granular cell tumors have a neural origin and, in immunohistochemical evaluations, they express S-100 and neuro...

full text

Tongue squamous cell carcinoma in a patient with systemic sclerosis: A case report

Objective: Systemic sclerosis (SS) is a chronic autoimmune disease of connective tissue, which involves skin and internal organs, and results in collagen deposition and fibroblasts activation. Studies have reported a higher risk of malignancy in patients with progressive systemic sclerosis (PSS).The aim of this study is to report a case of tongue squamous cell carcinoma (SCC) in a patient with ...

full text

Childhood tongue squamous cell carcinoma

BACKGROUND Tongue squamous cell carcinoma is a very rare disease in children with only a few cases reported in the literature. A case of 15 year old female tongue squamous cell carcinoma (SCC) with review of reported cases is presented. Pediatricians and family physicians should also be aware of the possibility of this disease entity occurring at an earlier age to decrease delay in diagnosis an...

full text

Clinical-pathological parameters in squamous cell carcinoma of the tongue.

The correlation between TNM classification and histological scores of malignancy, and the correlation of these parameters with the prognosis was evaluated in 16 cases of squamous cell carcinoma of the tongue. The cases were selected from the files of "Dr. Luiz Antônio" Cancer Hospital, Natal, RN, Brazil. After analysis of the patients' records, the data concerning TNM classification and prognos...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 9  issue 1

pages  28- 32

publication date 2014-01-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023