The Efficacy of Albendazole Mebendazole Combination Against Echinococcus granulosus Protoscoleces (an in vitro evaluation)
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the efficacy of albendazole mebendazole combination against echinococcus granulosus protoscoleces (an in vitro evaluation)
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full textA Comparison between the Effects of Albendazole and Mebendazole on the Enzymatic Activity of Excretory / Secretory Products of Echinococcus granulosus Protoscoleces in Vitro
BACKGROUND Hydatid cysts are formed in human body can be treated clinically by surgery or drugs such as albendazole (ABZ) and mebendazole (MBZ). The purpose of this study was comparing the effects of ABZ and MBZ on glutathione-S-transferase, alkaline phosphatase and protease enzymes activities in protoscoleces of hydatid cyst. METHODS The culture supernatants containing the parasite Excretory...
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full textStrain characterization of Echinococcus granulosus protoscoleces of cattle origin using the in vitro vesicular development.
The aim of this work was to characterize the strain of protoscoleces of E. granulosus of cattle origin using the in vitro vesicular development. The in vitro development of these samples was compared to samples of sheep origin determined previously by genetic analyses as common sheep strain (G1). There were similarities between sheep and cattle samples not only in the time of microcysts formati...
full textIn vitro effects of nitazoxanide on Echinococcus granulosus protoscoleces and metacestodes.
OBJECTIVES Infection of humans and domestic ruminants with the larval stage (metacestode) of Echinococcus granulosus results in cystic echinococcosis (CE). The metacestode causes a space-occupying lesion in visceral organs, most commonly in the liver. Benzimidazole carbamate derivatives, such as mebendazole and albendazole, are currently used for chemotherapeutic treatment of CE. In human patie...
full textCombined Effect of Flubendazole and Praziquantel on Echinococcus granulosus Protoscoleces and Microcysts
Background and objectives: Benzimidazoles such as albendazole are being used in some conditions to treat the hydatid disease, the common parasitic infections of humans and livestock that caused by Echinococcus granulosus. However, treatment with these drugs is not always with complete success. In this study we evaluate the in vitro efficacy of flubendazole (FLBZ) plus praziquantel (PZQ) against...
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volume 46.47 issue 1
pages 41- 45
publication date 1996-02-01
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