The effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats
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Abstract:
Objective(s): Particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. Fenvalerate is a pyrethroid insectide used in agriculture and has applications against a wide range of pests. This study was designed to evaluate the effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzyme activities in the presence of iodine and/or selenium deficiency on a rat model. Materials and Methods: Iodine and/or selenium deficiency was induced by feeding three-week-old Wistar rats with a diet containing
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the effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzymes in selenium and/or iodine deficient rats
objective(s): particularly in developing countries, selenium and/or iodine deficiencies are encountered and use of pesticides in agriculture are not well-controlled. fenvalerate is a pyrethroid insectide used in agriculture and has applications against a wide range of pests. this study was designed to evaluate the effects of fenvalerate on hepatic and cerebral xenobiotic metabolizing enzyme act...
full textAlterations in Cerebral Xenobiotic-Metabolizing Enzymes in Iodine and/or Selenium Deficient Rats
The aim of this study was to investigate the effects of iodine and/or selenium deficiency on cerebral enzyme levels/ activities responsible for xenobiotic metabolism on rats. Three-week old male Wistar rats were used and feeding period was 7-weeks. Selenium deficiency was introduced by a diet containing <0.005 mg/kg selenium, and iodine deficiency was produced by sodium perchlorate containing d...
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Journal title
volume 19 issue 10
pages 1040- 1048
publication date 2016-10-01
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